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Zhu P, Li SY, Ding J, Fei Z, Sun SN, Zheng ZH, Wei D, Jiang J, Miao JL, Li SZ, Luo X, Zhang K, Wang B, Zhang K, Pu S, Wang QT, Zhang XY, Wen GL, Liu JO, August JT, Bian H, Chen ZN, He YW. Combination -
Zeng Z, Yang A, Yang J, Zhang S, Xing Z, Wang X, Mei W, Jiang C, Lin J, Wu X, Xue Y, Wu Z, Yu L, Wang D, Chen J, Zheng S, Lin Q, Chen Q, Dong J, Zheng X, Wang J, Huang J, Chen Z, Chen P, Zheng M, Zhou -
This review critically evaluates neoantigen-based immunotherapy in hepatocellular carcinoma and highlights that low tumor mutational burden, limited neoantigen immunogenicity, and an immunosuppressive -
Combination immunotherapy of glioblastoma with dendritic cell cancer vaccines, antiPD-1 and poly I:CThis study establishes a synergistic immunotherapy paradigm in glioblastoma by integrating DC vaccine-mediated tumor-specific immune priming, PD-1 blockade-mediated T-cell reinvigoration, and Poly I:C -
A highly efficient needle-free-injection delivery system for mRNA-LNP vaccination against SARS-CoV-2This study demonstrates that needle-free injection enhances mRNA-LNP delivery through physical force–mediated transport while preserving nanoparticle integrity, mRNA encapsulation, and biological acti -
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This review summarizes the evolution of clinically approved combination immunotherapies and highlights the transition from single immune checkpoint blockade to multi-dimensional immune modulation, emp -
This Hepatology review provides a comprehensive analysis of the past limitations of tumor-associated antigen immunotherapy in hepatocellular carcinoma and highlights that advances in mRNA vaccine tech -
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This review elucidates the dynamics and protective roles of antibody responses during COVID-19 infection, demonstrating that effective vaccine development relies on high-quality antigen delivery and f -
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This study provides critical insights into cytokine-driven immunopathology in severe COVID-19 and highlights the importance of precise immune modulation rather than broad immunosuppression, offering v -
This study explored a personalized dendritic cell (DC) vaccine strategy based on tumor‑associated antigens (TAAs). It demonstrates that patient‑specific antigen selection combined with activation of p -
This study explored a personalized DC vaccine strategy based on tumor‑associated antigens (TAAs). It demonstrates that patient‑specific antigen selection and activation of professional antigen‑present -
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This study demonstrates the therapeutic potential of EGFRvIII-targeted CAR-T cells by exploiting a tumor-specific mutant antigen for selective immune-mediated killing -
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